Organometallic Compounds
Medchemexpress LLC Calcein (tetraethyl ester) | 1170856-93-5 | 99.5% | 25 MG
Calcein tetraethyl ester is a fluorescent dye utilized in biology for evaluating cell viability and facilitating short-term cellular labeling. Its ability to permeate cellular membranes allows for transport into live cells.
- Fluorescent dye for biological applications
- Enables cell viability testing
- Suitable for short-term cell labeling
- Permeates live cell membranes
- Useful in cell staining analysis
- Applied in in vivo imaging fluorescence
Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | ≥98.0% | 264.43 g·mol-1 | C12H28O4Si | 500 MG
TBDMS-PEG3-OH is a tert-butyldimethylsilyl (TBDMS)-protected PEG3 hydroxy derivative used as a linker or spacer in drug delivery and conjugation chemistry. It has formula C12H28O4Si, a molecular weight of 264.43 g·mol-1, and is provided at high purity for research use.
- used as a PEG linker for conjugation and spacer chemistry.
- TBDMS protection enables selective silyl-deprotection strategies.
- high purity (≥98.0%) suitable for research applications.
- available in multiple pack sizes for small- to medium-scale synthesis.
Medchemexpress LLC I-PEG5-OH 100mg
I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC HO-PEG3-(CH2)6-Cl | 1355955-95-1 | 95.0% | 268.78 g·mol⁻¹ | C12H25ClO4 | 10 MG
HO-PEG3-(CH2)6-Cl is a hydroxy-terminated PEG3 linker bearing a 6-chlorohexyl group, designed for assembling PROTACs and other bifunctional molecules. It serves as a spacer to connect targeting ligands and E3 ligase binders in targeted protein degradation research and is supplied for research use only.
- Hydroxy-terminated PEG3 spacer with a 6-chlorohexyl terminus.
- Designed for synthesis of PROTACs and bifunctional conjugates.
- Molecular formula C12H25ClO4; molecular weight 268.78 g·mol⁻¹.
- CAS number 1355955-95-1 for unambiguous identification.
- Reported purity about 95% from suppliers' product listings.
- Supplied in small milligram-scale packages for research synthesis.
eMolecules Azido-PEG5-triethoxysilane | | | 1g
Broadpharm | Azido-PEG5-triethoxysilane | 1g | 411413987 | BP-24074 | 98.000 | | | 538.714 | C22H46N4O9Si
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Medchemexpress LLC Azido-PEG3-SS-PEG3-azide | 1310827-27-0 | 99.3% | 468.59 | 50 MG
Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves are agents that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- A PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains an Azide group.
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules.
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing molecules.
eMolecules 2-(2-Aminoethylamino)-5-nitropyridine | 29602-39-9 | MFCD00006254 | 1g
Oakwood Chemical | 2-(2-Aminoethylamino)-5-nitropyridine | 1g | 537707239 | 099088 | | 29602-39-9 | MFCD00006254 | 182.183 | C7H10N4O2
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![Medchemexpress LLC 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate | 62921-74-8 | MFCD06200731 | 98.8% | 318.39 g/mol | C14H22O6S | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000210386.png-250.jpg)
Medchemexpress LLC 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate | 62921-74-8 | MFCD06200731 | 98.8% | 318.39 g/mol | C14H22O6S | 500 MG
m-PEG3-Tos is a tosyl-terminated polyethylene glycol (PEG) linker used as a reactive PEG3 spacer for conjugation and PROTAC synthesis. The tosyl leaving group enables nucleophilic substitution reactions to attach functional groups or linker arms in medicinal chemistry and bioconjugation workflows.
- Tosyl-terminated PEG3 linker for conjugation and PROTAC synthesis.
- Chemical name: 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate.
- CAS number: 62921-74-8.
- Molecular formula: C14H22O6S.
- Molecular weight: 318.39 g/mol.
- Purity: 98.8%.
- Package size: 500 MG.
Medchemexpress LLC Ethanamine, 2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]- | 1261350-60-0 | 95.0% | 267.79 | 25 MG
NH2-PEG3-C6-Cl is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism leverages the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC THP-PEG3-OH | 60221-37-6 | 98.7% | 10 G
THP-PEG3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are compounds that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker, with one ligand binding to an E3 ubiquitin ligase and the other to the target protein.
- PEG-based PROTAC linker
- Molecular formula: C11H22O5
- Molecular weight: 234.29
- Appearance: Liquid
- Color: Colorless to light yellow
- For research use only
- Target: PROTAC linkers
- Pathway: PROTAC
- Storage (pure form): -20°C for 3 years; 4°C for 2 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Tos-PEG5-Boc | 581065-94-3 | ≥97.0% | 5 G
Tos-PEG5-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand and a target protein ligand via a linker. It has a molecular weight of 476.58 and the formula C22H36O9S, appearing as a viscous liquid that is colorless to light yellow.
- PEG-based PROTAC linker
- Used for the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- Viscous liquid, colorless to light yellow appearance
Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 369.45 g/mol | C19H31NO6 | 100 MG
BCN-PEG3-OH is a BCN-functionalized PEG linker used for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and bioconjugation applications such as antibody-drug conjugate assembly. It provides a short PEG spacer with a reactive bicyclononyne moiety to enable site-selective conjugation without metal catalysts.
- Bcn functional group enables copper-free SPAAC click chemistry.
- Three-unit PEG spacer provides flexibility and solubility for conjugates.
- Suitable for antibody-drug conjugate synthesis and site-specific bioconjugation.
- Reactive alcohol terminus allows further functionalization or coupling reactions.
- Compact molecular weight and defined formula support precise stoichiometry in conjugation workflows.
Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | MFCD23726612 | >98.0% | 335.35 g/mol | C13H25N3O7 | 100 MG
Azido-PEG5-acid is an azide-terminated polyethylene glycol (PEG5) linker designed for click chemistry and bioconjugation. It features a terminal carboxylic acid and an azide functional group that enable copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), making it useful for PROTAC construction, ADC linker assembly, and general spacer chemistry.
- Azide-terminated PEG5 spacer for bioconjugation
- Compatible with CuAAC and SPAAC click reactions
- High purity for reliable coupling
- Colorless to light yellow liquid, easy to handle
- Stable under recommended storage conditions
Medchemexpress LLC Bis-PEG5-acid 10g | 439114-13-3 | 338.35 g/mol | C14H26O9 | 10 G
Bis-PEG5-acid is a polyethylene glycol (PEG) linker with two terminal carboxylic acid groups used to assemble PROTACs and other bifunctional molecules. The hydrophilic spacer increases aqueous solubility and provides flexible separation between ligands for conjugation chemistry.
- Two terminal carboxylic acid groups for conjugation.
- Hydrophilic PEG spacer improves solubility in aqueous media.
- Flexible linker suitable for PROTAC and bifunctional molecule assembly.
- Available in multiple package sizes including 10 G.
- Solid material with white to yellow appearance.